COMPOSITIONS FOR INHALATION

PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF A PHARMACEUTICALLY ACTIVE POLYPEPTIDE AND AN ENHANCER COMPOUND WHICH ENHANCES THE SYSTEMIC ABSORPTION OF THE POLYPEPTIDE IN THE LUNG OF A PATIENT, THE MIXTURE BEING IN THE FORM OF A DRY POWDER, IN WHICH AT LEAST 50OF THE TOTAL MASS OF POLYPEPTIDE A...

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Bibliographische Detailangaben
Hauptverfasser: BACKSTROM, KJELL GORAN ERIK, EDMAN, PETER, JOHANSSON, ANN CHARLOTTE BIRGIT, DAHLBACK, CARL MAGNUS OLOF
Format: Patent
Sprache:eng
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Zusammenfassung:PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF A PHARMACEUTICALLY ACTIVE POLYPEPTIDE AND AN ENHANCER COMPOUND WHICH ENHANCES THE SYSTEMIC ABSORPTION OF THE POLYPEPTIDE IN THE LUNG OF A PATIENT, THE MIXTURE BEING IN THE FORM OF A DRY POWDER, IN WHICH AT LEAST 50OF THE TOTAL MASS OF POLYPEPTIDE AND ENHANCER CONSISTS OF PRIMARY PARTICLES HAVING A DIAMETER LESS THAN OR EQUAL TO ABOUT 10 MICRONS, THE PRIMARY PARTICLES OPTIONALLY BEING FORMED INTO AGGLOMERATES; AND METHODS OF DELIVERING SUCH COMPOSITIONS BY INHALATION.(FIG.3)