COMPOSITIONS FOR INHALATION
PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF A PHARMACEUTICALLY ACTIVE POLYPEPTIDE AND AN ENHANCER COMPOUND WHICH ENHANCES THE SYSTEMIC ABSORPTION OF THE POLYPEPTIDE IN THE LUNG OF A PATIENT, THE MIXTURE BEING IN THE FORM OF A DRY POWDER, IN WHICH AT LEAST 50OF THE TOTAL MASS OF POLYPEPTIDE A...
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Format: | Patent |
Sprache: | eng |
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Zusammenfassung: | PHARMACEUTICAL COMPOSITIONS CONTAINING A MIXTURE OF A PHARMACEUTICALLY ACTIVE POLYPEPTIDE AND AN ENHANCER COMPOUND WHICH ENHANCES THE SYSTEMIC ABSORPTION OF THE POLYPEPTIDE IN THE LUNG OF A PATIENT, THE MIXTURE BEING IN THE FORM OF A DRY POWDER, IN WHICH AT LEAST 50OF THE TOTAL MASS OF POLYPEPTIDE AND ENHANCER CONSISTS OF PRIMARY PARTICLES HAVING A DIAMETER LESS THAN OR EQUAL TO ABOUT 10 MICRONS, THE PRIMARY PARTICLES OPTIONALLY BEING FORMED INTO AGGLOMERATES; AND METHODS OF DELIVERING SUCH COMPOSITIONS BY INHALATION.(FIG.3) |
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