PHARMACEUTICAL AGENTS

THE INVENTION PROVIDES A PHARMACEUTICAL COMPOSITION COMPRISING A PARTICULAR PHYSICAL FORM OF N-[4-[5-(CYCLOPENTYLOXY-CARBONYL)AMINO-1- METHYLINDOL-3-YL-METHYL]-3-METHOXYBENZOYL]-2-METHYL-BENZENESULPHONAMIDE AND POLYVINYLPYRROLIDONE. IT ALSO PROVIDES METHODS FOR PREPARING THIS PHYSICAL FORM, AND ANOT...

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Hauptverfasser:	RANDY JOHN BRADWAY, IEUAN JOHN EDWARDS, ROBERT JOSEPH TIMKO, JAMES JOSEPH HOLOHAN, ARLENE CLEMENTS
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	THE INVENTION PROVIDES A PHARMACEUTICAL COMPOSITION COMPRISING A PARTICULAR PHYSICAL FORM OF N-[4-[5-(CYCLOPENTYLOXY-CARBONYL)AMINO-1- METHYLINDOL-3-YL-METHYL]-3-METHOXYBENZOYL]-2-METHYL-BENZENESULPHONAMIDE AND POLYVINYLPYRROLIDONE. IT ALSO PROVIDES METHODS FOR PREPARING THIS PHYSICAL FORM, AND ANOTHER PHYSICAL FORM OF N-[4-[5-(CYCLOPENTYLOXYCARBONYL)AMINO-1-METHYLINDOL-3-YL-METHYL]-3-METHOXYBENZOYL]-2-METHYLBENZENESULPHONAMIDE USEFUL IN THE PREPARATION OF THE FIRST MENTIONED PHYSICAL FORM. THE COMPOSITIONS ARE USEFUL IN THE TREATMENT OF DISEASES IN WHICH LEUKOTRIENES ARE IMPLICATED, FOR EXAMPLE ASTHMA.