HYDROXYLAMINE SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS

HYDROXYLAMINE SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS

Imidazo-containing compounds (e.g., imidazoquinolines, imidazonaphthyridines, imidazopyridines) with a hydroxylamine substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine bi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: BERNHARD M. ZIMMERMANN
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Imidazo-containing compounds (e.g., imidazoquinolines, imidazonaphthyridines, imidazopyridines) with a hydroxylamine substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed. Se describen compuestos que contienen imidazo (por ejemplo, imidazoquinolinas, imidazonaftiridinas, imidazopiridinas) con un sustituyente hidroxilamina en la posicion 1, composiciones farmaceuticas que contienen los compuestos, intermediarios, y metodos de uso de estos compuestos como inmunomoduladores, para inducir la biosintesis de citoquina en animales y para el tratamiento de enfermedades que incluyen enfermedades virales y neoplasicas.