FUNCTIONALLY RECONSTITUTED VIRAL MEMBRANES CONTAINING ADJUVANT

The present invention relates to vaccines directed against antigens such as membrane proteins from pathogens or tumor cells. The invention further relates to methods of forming reconstituted viral membranes, with membrane fusion activity, which are lipid bilayer membranes preferably containing natural lipids of a virus, a viral fusion protein, one or more optional further antigens as well as amphiphilic adjuvants. Pharmaceutical compositions comprising such reconstituted viral membranes are also part of the invention. La presente invencion se relaciona con vacunas prescritas contra antigenos tales como por ejemplo, proteinas membranosas provenientes de patogenos o celulas tumorales. La invencion tambien se relaciona con los metodos para formar membranas virales reconstituidas, con actividad para fusion de membranas, que son membranas bicapa lipidicas que contienen de preferencia lipidos naturales de un virus, una proteina de fusion viral, uno o mas antigenos opcionales, adicionales asi como tambien, adyuvantes anfifilicos. Las composiciones farmaceuticas que comprenden estas membranas virales reconstituidas tambien forman parte de la invencion.