HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS

The present invention relates to pharmaceutical compositions comprising compounds of the Formula I, or a pharmaceutically acceptable salt thereof, and methods of selectively inhibiting or antagonizing the alphanubeta3 and/or the alphanubeta5 integrin without significantly inhibiting the alphanubeta6...

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1. Verfasser: DESAI, BIPINCHANDRA N
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to pharmaceutical compositions comprising compounds of the Formula I, or a pharmaceutically acceptable salt thereof, and methods of selectively inhibiting or antagonizing the alphanubeta3 and/or the alphanubeta5 integrin without significantly inhibiting the alphanubeta6 integrin. La presente invencion se refiere a composiciones farmaceuticas que comprenden compuestos de la formula l, o una sal farmaceuticamente aceptable del mismo, y metodos para inhibir o antagonizar selectivamente la integrina av¦3 y/o av¦5 sin inhibir significativamente la integrina av¦6.