QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS ANTIMUSCARINIC AGENTS

The invention features quaternary ammonium compounds of formula (I), and any stereoisomers thereof, wherein R1 is selected from C1-C6 alkyl, -CH2-(C1-C4 alkenyl), and -CH2-(C1-C6 alkynyl), each of which is optionally substituted with a group selected from phenyl, C1-C4 alkoxy, and hydroxyl; and X re...

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1. Verfasser: MARTIN DURHAM MEGLASSON
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The invention features quaternary ammonium compounds of formula (I), and any stereoisomers thereof, wherein R1 is selected from C1-C6 alkyl, -CH2-(C1-C4 alkenyl), and -CH2-(C1-C6 alkynyl), each of which is optionally substituted with a group selected from phenyl, C1-C4 alkoxy, and hydroxyl; and X represents an anion of a pharmaceutically acceptable acid, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. La invencion presenta compuestos de amonio cuaternario de formula I, descritos en la presente memoria y su uso en el tratamiento de: asma, trastorno pulmonar obstructivo cronico, rinitis alergica y rinitis infecciosa.