BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS

This invention relates to novel compounds, which are thyroid receptor ligands, and to methods of preparing such compounds. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: RYONO, DENIS, EVAN
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:This invention relates to novel compounds, which are thyroid receptor ligands, and to methods of preparing such compounds. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described herein is administered in a therapeutically effective amount. Esta invencion se refiere a compuestos novedosos, que son ligandos del receptor tiroide, y a metodos para preparar tales compuestos. Ademas, se proporciona un metodo para prevenir, inhibir o tratar enfermedades o trastornos asociados con la disfuncion del metabolismo o que dependen de la expresion de un gen regulado por T3, en donde el compuesto como se describe en la presente se administra en una cantidad terapeuticamente efectiva.