NOVEL USES OF CEPHAIBOLS

The invention relates to the use of compounds of general formula AcPhe -Aib -Aib- Aib -x -w -Leu -y -Aib -Hyp -Gln -z -Hyp -Aib -Pro-R, in which R represents Phe-ol or Phe-al and w, x, y, and z have the following meaning: a) w represents Gly or Ala; x represents Aib, and y and z represent Iva; b) w...

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1. Verfasser: UDO GRAEFE
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The invention relates to the use of compounds of general formula AcPhe -Aib -Aib- Aib -x -w -Leu -y -Aib -Hyp -Gln -z -Hyp -Aib -Pro-R, in which R represents Phe-ol or Phe-al and w, x, y, and z have the following meaning: a) w represents Gly or Ala; x represents Aib, and y and z represent Iva; b) w represents Gly; x, y, and z represent Iva; c) w represents Gly; x and z represent Aib, and y represents Iva; d) w represents Gly; x, y, and z represent Aib; or e) w represents Gly; x and y represent Aib, and z represents Iva; or of general formula AcPhe -Iva -Gln -Aib -Ile -Thr -Aib -Leu -Aib- x -Gln -Aib -Hyp -Aib -Pro -Phe -Ser, in which x represents Hyp or Pro, and the physiologically acceptable salts thereof for producing a medicament having a neurological and/or immunosuppressive effect. La invencion se refiere al uso de los compuestos de la formula general AcPhe- Aib -Aib -Aib -x -w- Leu -y -Aib -Hyp -Gln -z -Hyp -Aib -Pro- R, en los cuales R representa Phe-ol o Phe-Al, y w, x, y y z tienen el siguiente significado: a) w representa Gly; x y z representan Aib, y y representa Iva; d) w representa Gly; x, y y z representan Aib; o e) w representa Gly; x y y representan Aib, y z representa Iva; o de la formula general AcPhe -Iva -Gln -Aib-Ile -Thr -Aib -Leu -Aib -x -Gln -Aib- Hyp -Aib -Pro -Phe -Ser, en la cual x representa Hyp o Pro, y las sales aceptadas para uso fisiologico de estos para producir un medicamento que tiene un efecto neurologico y/o inmunosupresor.