CONTROLLED RELEASE PHARMACEUTICAL DOSAGE FORMS OF A CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITOR

The present invention relates to controlled release pharmaceutical dosage forms of a cholesteryl ester transfer protein inhibitor, (CETPI) methods of using and methods of making same. In particular, it relates to a controlled release form of the CETPI [2R, 4S] 4-[(3, 5-bis-trifluoromethyl -benzyl)- methodyycarbonyl -amino]-2 -ethyl-6- trifluoromethyl -3, 4-dihydro- 2H-quinoline -1-carboxylic acid ethyl ester. La presente invencion se refiere a formas de dosificacion farmaceutica de liberacion controlada de un inhibidor de proteina de transferencia de ester de colesterilo (CETPI), a procedimientos de uso y a procedimientos de preparacion de las mismas. En particular, se refiere a una forma de liberacion controlada del CETPI ester etilico del acido [2R,4S]-4- [(3, 5-bistrifluorometilbencil) metoxicarbonilamino]-2-etil- 6-trifluorometil- 3, 4-dihidro-2H- quinolin-1 -carboxilico.