SUCRALOSE FORMULATIONS TO MASK UNPLEASANT TASTES

The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases. La presente invencion esta dirigida a una base excipiente liquida farmaceuticamente aceptable para disimular sabor para la administracion de una cantidad relativamente amplia de medicinas con sabor desagradable. Mas particularmente, se provoca aumentar la dulzura y tener el efecto de disimular el sabor por la adicion de sucralosa a la base excipiente con el mantenimiento de un pH de 2 a 5. La invencion ademas esta dirigida a composiciones medicinales que comprenden la base excipiente liquida y medicinas con sabor desagradable. Ademas, la invencion se dirige a un metodo para disimular el sabor desagradable de medicinas a traves de su incorporacion a las bases excipientes liquidas.