WET MILLING PROCESS

WET MILLING PROCESS

A process for preparing a finely divided preparation of a drug substance comprising wet milling a suspension of the drug substance in a mill having at least one chamber and agitation means, said chamber(s) and/or said agitation means comprising nylon, wherein the nylon comprises one or more internal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: LEONARD, GRAHAM, STANLEY
Format: Patent
Sprache:eng ; spa
Schlagworte:
CRUSHING, PULVERISING, OR DISINTEGRATING
CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
MILLING GRAIN
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PREPARATORY TREATMENT OF GRAIN FOR MILLING
TRANSPORTING
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Beschreibung
Zusammenfassung:A process for preparing a finely divided preparation of a drug substance comprising wet milling a suspension of the drug substance in a mill having at least one chamber and agitation means, said chamber(s) and/or said agitation means comprising nylon, wherein the nylon comprises one or more internal lubricants results in finely divided preparations of a drug substance in which the level of grinding media contamination and process contamination are reduced.