METHODS AND APPARATUS FOR PROCESSING TEMPERATURE SENSITIVE MATERIALS

A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels (20). Ultrasonic energy from ultrasonic drivers (42) is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated product. The ultrasonic energy prevents the growth of dendrites on the crystals, resulting in the formation and removal of small crystals of the component to be removed without damage to or removal of the remaining components. Methods and apparatuses for cryoprecipitation and chromatography are also disclosed. Se describen un metodo y sistema para remover selectivamente un componente de un material concentrando de esta manera otros componentes del material. El material es enfriado debajo de la temperatura de fusion del material para formar una fase liquida superenfriada con la placa de transferencia termica con canales de enfriamiento. La energia ultrasonica desde los impulsores ultrasonicos es aplicada al material para formar los cristales de fase solida del componente que se va a remover. Esos cristales son removidos para dejar el producto concentrado. L a energia ultrasonica evita el crecimiento de dendritas sobre los cristales, resultando en la formacion y remocion de pequenos cristales del componente que se va a remover sin dano a o remocion de los componentes restantes. Se describen tambien los metodos y aparatos para la crioprecipitacion y cromatografia.