PRIMARY SEQUENCE AND cDNA OF TOXINS HAVING ACTIVITY OF CENTRUROIDES GENUS SCORPIONS

The present invention provides a novel amino acid sequence of toxins from Centruroides genus scorpions, which is effective against insects, but non-toxic for mammals. These basic polypeptides comprise from 60 to 70 amino acids, eight cisteine residues in equivalent positions, and show a similarity o...

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Bibliographische Detailangaben
Hauptverfasser: CONSUELO GARCIA RODRIGUEZ, FERNANDO ZAMUDIO ZUNIGA, BALTAZAR BECERRIL LUJAN, BARBARA SELISKO, ANGELINA RAMIREZ NAVARRO, LOURIVAL DOMINGOS POSSANI POST
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention provides a novel amino acid sequence of toxins from Centruroides genus scorpions, which is effective against insects, but non-toxic for mammals. These basic polypeptides comprise from 60 to 70 amino acids, eight cisteine residues in equivalent positions, and show a similarity of 59 percent. The present invention further provides a novel cDNA sequence which encode for one of the toxins herein disclosed. La presente invencion provee una secuencia de aminoácidos de toxinas novedosa de alacranes del género Centruroides que son efectivas contra insectos, pero no toxicas para mamíferos. Estos polipéptidos básicos comprenden de 60 a 70 aminoácidos, contienen ocho residuos de cisteína en posiciones equivalentes y muestran una similitud de 59%. Asimismo, la presente invencion provee una secuencia novedosa de ADNc que codifica para una de las toxinas de esta invencion.