ACIDOS CARBOXILICOS OPTICAMENTE ACTIVOS, PROCESO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN

The present invention relates to R- and S-carboxylic acids of the formula I in which R1 denotes an aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl or arylamino radical, where the aryl moieties can each be substituted by one or more radicals from the group consisting of hydroxyl, halogen, C1-C8-alkyl, C1-C8-alkoxy, trifluoromethyl, cyano, nitro, amino, C1-C8-alkylamino and di-C1-C8-alkylamino, R2 denotes an aryl radical which can be substituted by one or more radicals from the group consisting of hydroxyl, halogen, C1-C8-alkyl, C1-C8-alkoxy, trifluoromethyl, cyano, nitro, amino, C1-C8-alkylamino or di-C1-C8-alkylamino, A denotes a straight-chain or branched, saturated or unsaturated aliphatic radical having 3-10 carbon atoms, which is optionally interrupted by a hetero atom, with the proviso that there should not be a hetero atom on an unsaturated aliphatic carbon atom, Y denotes the groups -S(O)n- or -O-, n denotes the numbers 0, 1 or 2 and B denotes a valency line or a straight-chain or branched, saturated or unsaturated aliphatic radical having 1 to 5 carbon atoms, and their physiologically acceptable salts and esters. The present invention also relates to medicinal preparations containing compounds of the formula I for the treatment of diabetes, prediabetes and in particular for the treatment of adult-onset diabetes. Additionally, the substances according to the invention exhibit a pronounced hypolipodaemic action and are therefore also suitable for the treatment of disorders of fat metabolism.