FACTOR DEL CRECIMIENTO DEL FIBROBLASTO BASICO HUMANO RECOMBINANTE Y METODO PARA SU OBTENCION

Recombinant human basic fibroblast growth factors or functionally equivalent analogs thereof are provided in which at least one of the four cysteine amino acid residues is derivatized. Usually the two cysteines corresponding to those present in positions 69 and 87 of the 146 amino acid form of the n...

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Bibliographische Detailangaben
Hauptverfasser:	GIAMPAOLO NITTI, PAOLO CACCIA, GILLES CAUET, FEDERICO BERTOLERO
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Recombinant human basic fibroblast growth factors or functionally equivalent analogs thereof are provided in which at least one of the four cysteine amino acid residues is derivatized. Usually the two cysteines corresponding to those present in positions 69 and 87 of the 146 amino acid form of the natural human basic fibroblast growth factor are derivatized by moieties such as for example -CH2COOH or -CH2CONH2. Such derivatized recombinant human basic fibroblast growth factors may be used for the healing of wounds, ulcers or burns; regeneration of damaged neural tissues; aiding tissue transplant or healing bone graft; or revascularization of ischaemic tissues.