PROCEDIMIENTO PARA LA PRODUCCION DE 4-PREGNENO-3,20-DION Y PRODUCTOS DERIVADOS

PCT No. PCT/DE91/00620 Sec. 371 Date Jun. 18, 1992 Sec. 102(e) Date Jun. 18, 1992 PCT Filed Jul. 30, 1991 PCT Pub. No. WO92/03571 PCT Pub. Date Mar. 5, 1992.A process for the production of 4-pregnene-3,20-dione and its derivatives of general formula I (I) in which R1 means a hydrogen atom, a fluorin...

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Hauptverfasser:	ALFRED WEBER, MARIO KENNECKE
Format:	Patent
Sprache:	spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS SPIRITS VINEGAR WINE
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Zusammenfassung:	PCT No. PCT/DE91/00620 Sec. 371 Date Jun. 18, 1992 Sec. 102(e) Date Jun. 18, 1992 PCT Filed Jul. 30, 1991 PCT Pub. No. WO92/03571 PCT Pub. Date Mar. 5, 1992.A process for the production of 4-pregnene-3,20-dione and its derivatives of general formula I (I) in which R1 means a hydrogen atom, a fluorine atom or a methyl group, R2 represents a hydrogen atom or a hydroxy group, and R3 and R4 together symbolize a carbon-carbon bond or R3 represents a hydrogen atom, a hydroxy group or an alkanoyloxy group with up to 6 carbon atoms and R4 means a hydrogen atom or a methyl group, is described, which is characterized in that a pregnane derivative of general formula II (II) in which R1, R3 and R4 have the above-mentioned meaning, symbolizes a single bond or a double bond, R5 represents a hydrogen atom, a hydroxy group or an alkanoyloxy group with at most 6 carbon atoms and R6 means a hydrogen atom or an alkanoyl group with at most 6 carbon atoms, is fermented with a bacterial culture of species Mycobacterium spec. NRRL B-3805.