TETRAHYDROQUINOLINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein. La presente invención se refiere a...

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Bibliographische Detailangaben

Hauptverfasser:	Katherine J. KAYSER-BRICKER, George P. LUKE, David S. MILLAN, Shawn E. R. SCHILLER, Kenneth W. BAIR, Goss Stryker KAUFFMAN, Matthew W. MARTIN, Torsten HERBERTZ, Adam C. TALBOT
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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