PROCESS FOR MAKING TABLET USING RADIOFREQUENCY AND LOSSY COATED PARTICLES
In one aspect the present invention features process for making a tablet comprising at least one pharmaceutically active agent, said method comprising the step of applying radiofrequency energy to a powder blend to sinter said powder blend into said tablet, wherein said powder blend comprises lossy...
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Format: | Patent |
Sprache: | eng ; spa |
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Zusammenfassung: | In one aspect the present invention features process for making a tablet comprising at least one pharmaceutically active agent, said method comprising the step of applying radiofrequency energy to a powder blend to sinter said powder blend into said tablet, wherein said powder blend comprises lossy coated particles and said at least one pharmaceutically active agent, wherein said lossy coated particles comprises a substrate that is at least partially coated with a lossy coating comprising at least one activator, wherein said substrate has a Q value of greater than 100 and said activator has a Q value of less than 75.
En un aspecto, la presente invención presenta un proceso para elaborar una tableta que comprende al menos un agente farmacéuticamente activo, ese método comprende la etapa de aplicar energía de radiofrecuencia a una mezcla en polvo para sinterizar la mezcla en polvo en la tableta, en donde la mezcla de polvo comprende partículas disipativas revestidas y el al menos un agente farmacéuticamente activo, en donde las partículas disipativas revestidas comprenden un sustrato que está al menos parcialmente revestido con un revestimiento disipativo que comprende al menos un activador, en donde el sustrato tiene un valor Q de mayor que 100 y ese activador tiene un valor Q de menor que 75. |
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