INDAZOLE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS

The present invention relates to novel indazole compounds of the Formula (I), wherein, R1 is alkyl or cycloalkyl; (Formula II) including their stereoisomers and their pharmaceutically acceptable salts. This invention also relates to methods of making such compounds and pharmaceutical compositions co...

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Bibliographische Detailangaben
Hauptverfasser:	SHINDE, Anil Karbhari, NIGORI, Ramakrishna, MOHAMMED, Abdul Rasheed, JASTI, Venkateswarlu, Shankar Reddy GAGGINAPALLY
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel indazole compounds of the Formula (I), wherein, R1 is alkyl or cycloalkyl; (Formula II) including their stereoisomers and their pharmaceutically acceptable salts. This invention also relates to methods of making such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to 5-Hydroxytryptamine 4 (5-HT4) receptor agonists. La presente invención se relaciona con compuestos de indazol novedosos de la fórmula (I), incluyendo sus estereoisómeros y sus sales farmacéuticamente aceptables. La presente invención también se relaciona con métodos de elaboración de tales compuestos y de composiciones farmacéuticas que comprenden dichos compuestos. Los compuestos de la presente invención son útiles en el tratamiento de varios trastornos que se relacionan con agonistas de receptores de 5-hidroxitriptamina 4 (5-HT4). (Ver fórmula).