NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES

The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antith...

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Bibliographische Detailangaben
Hauptverfasser:	TOMISLAV KAROLI, KENNETH DAVID JOHNSTONE, EDWARD TIMOTHY HAMMOND, LIGONG LIU, PAUL NEWTON HANDLEY, VITO FERRO, NORBERT WIMMER
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS SUGARS
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Beschreibung
Zusammenfassung:	The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment of a mammalian subject. La presente invención describe compuestos novedosos que son útiles como inhibidores de proteínas de enlace de sulfato heparan; composiciones que comprenden los compuestos, y el uso de los compuestos y composiciones de los mismos para el tratamiento antiangiogénico, antimetástico, antiinflamatorio, antimicrobial, anticoagulante y/o antitrombótico de un sujeto mamífero.