DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS
The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions fo...
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| creator | THENNATI, RAJAMANNAR SENGUPTA, PRABAL CHITTURI, TRINADHA RAO PURI, CHETAN SURJITSINGH DESAI, DIPALI MANUBHAI CHIMANWALA, SABBIRHUSEN YUSUFBHAI MEHTA, VARUN ANILKUMAR CHOKSHI, HEMANT ASHVINBHAI |
| description | The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals.
La presente invención se relaciona con compuestos de hidrazida diarilacetileno de la formula (I) o una sal farmacéuticamente aceptable del mismo, como los inhibidores de quinasa tirosina, el proceso para su preparación, y para el uso de los compuestos de la formula (I) en la preparación de las composciciones farmacéuticas para el tratamiento terapéutico o trastornos relacionados con las quinasas de tirosina, en animales de sangre caliente. |
| format | Patent |
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La presente invención se relaciona con compuestos de hidrazida diarilacetileno de la formula (I) o una sal farmacéuticamente aceptable del mismo, como los inhibidores de quinasa tirosina, el proceso para su preparación, y para el uso de los compuestos de la formula (I) en la preparación de las composciciones farmacéuticas para el tratamiento terapéutico o trastornos relacionados con las quinasas de tirosina, en animales de sangre caliente.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160107&DB=EPODOC&CC=MX&NR=336051B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160107&DB=EPODOC&CC=MX&NR=336051B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THENNATI, RAJAMANNAR</creatorcontrib><creatorcontrib>SENGUPTA, PRABAL</creatorcontrib><creatorcontrib>CHITTURI, TRINADHA RAO</creatorcontrib><creatorcontrib>PURI, CHETAN SURJITSINGH</creatorcontrib><creatorcontrib>DESAI, DIPALI MANUBHAI</creatorcontrib><creatorcontrib>CHIMANWALA, SABBIRHUSEN YUSUFBHAI</creatorcontrib><creatorcontrib>MEHTA, VARUN ANILKUMAR</creatorcontrib><creatorcontrib>CHOKSHI, HEMANT ASHVINBHAI</creatorcontrib><title>DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS</title><description>The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals.
La presente invención se relaciona con compuestos de hidrazida diarilacetileno de la formula (I) o una sal farmacéuticamente aceptable del mismo, como los inhibidores de quinasa tirosina, el proceso para su preparación, y para el uso de los compuestos de la formula (I) en la preparación de las composciciones farmacéuticas para el tratamiento terapéutico o trastornos relacionados con las quinasas de tirosina, en animales de sangre caliente.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB38XQMivRxdHYNifRx9XNV8Ih0CXKM8nRxVXD29wtx9PTz9HNXCIkM8g_2BMp6e_o5BrsqePp5eDp5hvgHBfMwsKYl5hSn8kJpbgY5N9cQZw_d1IL8-NTigsTk1LzUknjfCGNjMwNTQydjggoAzwUpzg</recordid><startdate>20160107</startdate><enddate>20160107</enddate><creator>THENNATI, RAJAMANNAR</creator><creator>SENGUPTA, PRABAL</creator><creator>CHITTURI, TRINADHA RAO</creator><creator>PURI, CHETAN SURJITSINGH</creator><creator>DESAI, DIPALI MANUBHAI</creator><creator>CHIMANWALA, SABBIRHUSEN YUSUFBHAI</creator><creator>MEHTA, VARUN ANILKUMAR</creator><creator>CHOKSHI, HEMANT ASHVINBHAI</creator><scope>EVB</scope></search><sort><creationdate>20160107</creationdate><title>DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS</title><author>THENNATI, RAJAMANNAR ; SENGUPTA, PRABAL ; CHITTURI, TRINADHA RAO ; PURI, CHETAN SURJITSINGH ; DESAI, DIPALI MANUBHAI ; CHIMANWALA, SABBIRHUSEN YUSUFBHAI ; MEHTA, VARUN ANILKUMAR ; CHOKSHI, HEMANT ASHVINBHAI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX336051B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>THENNATI, RAJAMANNAR</creatorcontrib><creatorcontrib>SENGUPTA, PRABAL</creatorcontrib><creatorcontrib>CHITTURI, TRINADHA RAO</creatorcontrib><creatorcontrib>PURI, CHETAN SURJITSINGH</creatorcontrib><creatorcontrib>DESAI, DIPALI MANUBHAI</creatorcontrib><creatorcontrib>CHIMANWALA, SABBIRHUSEN YUSUFBHAI</creatorcontrib><creatorcontrib>MEHTA, VARUN ANILKUMAR</creatorcontrib><creatorcontrib>CHOKSHI, HEMANT ASHVINBHAI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THENNATI, RAJAMANNAR</au><au>SENGUPTA, PRABAL</au><au>CHITTURI, TRINADHA RAO</au><au>PURI, CHETAN SURJITSINGH</au><au>DESAI, DIPALI MANUBHAI</au><au>CHIMANWALA, SABBIRHUSEN YUSUFBHAI</au><au>MEHTA, VARUN ANILKUMAR</au><au>CHOKSHI, HEMANT ASHVINBHAI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS</title><date>2016-01-07</date><risdate>2016</risdate><abstract>The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals.
La presente invención se relaciona con compuestos de hidrazida diarilacetileno de la formula (I) o una sal farmacéuticamente aceptable del mismo, como los inhibidores de quinasa tirosina, el proceso para su preparación, y para el uso de los compuestos de la formula (I) en la preparación de las composciciones farmacéuticas para el tratamiento terapéutico o trastornos relacionados con las quinasas de tirosina, en animales de sangre caliente.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS |
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