DIARYLACETYLENE HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS

The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions fo...

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Hauptverfasser: THENNATI, RAJAMANNAR, SENGUPTA, PRABAL, CHITTURI, TRINADHA RAO, PURI, CHETAN SURJITSINGH, DESAI, DIPALI MANUBHAI, CHIMANWALA, SABBIRHUSEN YUSUFBHAI, MEHTA, VARUN ANILKUMAR, CHOKSHI, HEMANT ASHVINBHAI
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention relates to novel diarylacetylene hydrazide compounds of formula (I) or pharmaceutically acceptable salt thereof, as tyrosine kinase inhibitors, the process for their preparation, and to the use of the compounds of formula (I) in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders related to tyrosine kinases, in warm-blooded animals. La presente invención se relaciona con compuestos de hidrazida diarilacetileno de la formula (I) o una sal farmacéuticamente aceptable del mismo, como los inhibidores de quinasa tirosina, el proceso para su preparación, y para el uso de los compuestos de la formula (I) en la preparación de las composciciones farmacéuticas para el tratamiento terapéutico o trastornos relacionados con las quinasas de tirosina, en animales de sangre caliente.