COMPOSITION FOR PREVENTING OR TREATING DENTAL CARIES

The present invention relates to a pharmaceutical composition for preventing or treating dental caries, and a use thereof. The pharmaceutical composition according to the present invention includes a peptide comprising an amino acid sequence of General Formula 1 as an active ingredient: K-Y-R1-R2-R3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GUG Hye Ri, PARK Joo Hwang, LEE Dong Seol
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The present invention relates to a pharmaceutical composition for preventing or treating dental caries, and a use thereof. The pharmaceutical composition according to the present invention includes a peptide comprising an amino acid sequence of General Formula 1 as an active ingredient: K-Y-R1-R2-R3-R4-R5-R6-R7-R8 (General Formula 1). In General Formula 1, R1 is arginine (R), lysine (K), or glutamine (Q), R2 is arginine (R) or glutamine (Q), R3, R4, and R5 are each arginine (R) or lysine (K), R6 is asparagine (N) or serine(S), and R7 and R8 are lysine (K) or tyrosine (Y). La presente invención se refiere a una composición farmacéutica para prevenir o tratar la caries dental y el uso de la misma. La composición farmacéutica, de acuerdo con la presente invención, incluye un péptido que comprende una secuencia de aminoácidos de la Fórmula General 1 como principio activo: K-Y-R1-R2-R3-R4-R5-R6- R7-R8 (Fórmula General 1). En la Fórmula General 1, R1 es arginina (R), lisina (K) o glutamina (Q), R2 es arginina (R) o glutamina (Q), R3, R4 y R5 son cada uno arginina (R) o lisina (K), R6 es asparagina (N) o serina (S), y R7 y R8 son lisina (K) o tirosina (Y).