BIOCATALYTIC SYNTHESIS OF (1S,3S)-3-HYDROXYCYCLOHEXANE-1-CARBOXYL IC ACID COMPOUNDS

Improved methods and intermediates thereof for preparing (1S,3S)-3-hydroxycyclohexane-1-carboxylic acid are described. These compounds are useful as intermediates for making carbamoyloxymethyl triazole cyclohexyl acid LPA antagonists. Se describen métodos mejorados y sus compuestos intermediarios pa...

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Hauptverfasser:	TAN Yichen, MCKENNA Shane, JOE Candice Lee, FOX Richard J, SMITH Michael J, GEORGE David Thomas
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY SPIRITS VINEGAR WINE
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Zusammenfassung:	Improved methods and intermediates thereof for preparing (1S,3S)-3-hydroxycyclohexane-1-carboxylic acid are described. These compounds are useful as intermediates for making carbamoyloxymethyl triazole cyclohexyl acid LPA antagonists. Se describen métodos mejorados y sus compuestos intermediarios para preparar el ácido (1S,3S)-3-hidroxiciclohexano-1-carboxílico. Estos compuestos son útiles como compuestos intermediarios para preparar antagonistas de LPA del ácido carbamoiloximetiltriazol ciclohexílico.