COMBINATIONS OF STAT-INHIBITORS AND IMMUNE CHECKPOINT INHIBITORS FOR THE TREATMENT AND/OR MANAGEMENT OF CANCER

Provided herein are methods of treating a cancer in a subject in need thereof, comprising administering to the subject an effective amount of a STAT inhibitor and an effective amount of an immune checkpoint inhibitor (e.g., PD-1 inhibitor or PD-L1 inhibitor). Se proporcionan en la presente métodos p...

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Bibliographische Detailangaben
Hauptverfasser:	DE ACHAVAL Sofia, ALIBHAI Imran, GYURIS Jeno
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods of treating a cancer in a subject in need thereof, comprising administering to the subject an effective amount of a STAT inhibitor and an effective amount of an immune checkpoint inhibitor (e.g., PD-1 inhibitor or PD-L1 inhibitor). Se proporcionan en la presente métodos para tratar un cáncer en un sujeto que lo necesite, que comprenden la administración al sujeto de una cantidad eficaz de un inhibidor de STAT y una cantidad eficaz de un inhibidor del punto de control inmunitario (por ejemplo, un inhibidor de PD-1 o un inhibidor de PD-L1).