QUINOLINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS

The present disclosure provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic method...

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Bibliographische Detailangaben
Hauptverfasser:	BLOMGREN Peter A, PATEL Leena, TREIBERG Jennifer Anne, PERREAULT Stephane, SEEGER Natalie, STEVENS Kirk L, CAMPBELL Taryn, YEUNG Suet C, CHANDRASEKHAR Jayaraman, ZHAO Zhongdong, SEDILLO Kassandra F, NAVA Nicole, CODELLI Julian A, CURRIE Kevin S, PERRY Jason K, KROPF Jeffrey E, CLARK Christopher T, MOAZAMI Yasamin
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease. La presente invención se refiere a un compuesto de fórmula (I): (ver Fórmula) (I); o una sal farmacéuticamente aceptable del mismo como se describe en el presente documento. La presente divulgación también proporciona composiciones farmacéuticas que comprenden un compuesto de Fórmula (I), procesos para preparar compuestos de Fórmula (I) y métodos terapéuticos para tratar enfermedades inflamatorias.