PROCESSES FOR THE PREPARATION OF 1,2,3,5,6,7-HEXAHYDRO-S-INDACENE DERIVATIVES

The present invention relates to intermediates and processes useful for preparing 1-ethyl-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)pipe ridine-4-sulfonamide and salts thereof. The present invention further relates to 1-ethyl-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)pipe ridine-4-sulfonamide and salts thereof when prepared by such processes and to associated pharmaceutical compositions and uses for the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition. La presente invención se refiere a intermediarios y procesos útiles para preparar 1-etil-N-((1,2,3,5,6,7ahidro-s-indacen-4-il)c arbamoil)piperidin-4-sulfonamida y sales de esta. La presente invención se refiere además a 1- etil-N-((1,2,3,5,6,7-hexahidro-s- indacen-4-il)carbamoil)piperidin-4-sulfonamida y sales de esta cuando se prepara mediante tales procesos y a composiciones farmacéuticas y usos para el tratamiento y la prevención de trastornos médicos y enfermedades, más especialmente mediante inhibición de NLRP3.