RAS INHIBITORS

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers. La divulgación presenta compuestos macrocíclicos, y composiciones farmacéuticas y complejos proteicos de estos...

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Hauptverfasser:	KOLTUN Elena, S, CREGG James, LIU Yang, BURNETT G., Leslie, KNOX John, E, GILL Adrian, L
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers. La divulgación presenta compuestos macrocíclicos, y composiciones farmacéuticas y complejos proteicos de estos, capaces de inhibir las proteínas Ras, y sus usos en el tratamiento de cánceres.