TYK2 DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same. Compounds and compositions thereof that are useful, for example, for targeting, inhibiting, and/or degrading TYK2. In certain embodiments, provided are TYK2 inhibitors and/or degraders and methods of makin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PENNINGTON Lewis Dale, YATES Christopher Michael, FORD Melissa, COMER Eamon, MARX Isaac, ZHU Xiao
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The present invention provides compounds, compositions thereof, and methods of using the same. Compounds and compositions thereof that are useful, for example, for targeting, inhibiting, and/or degrading TYK2. In certain embodiments, provided are TYK2 inhibitors and/or degraders and methods of making same. More specifically, TYK2 degraders, compositions which comprise TYK2 degraders, and methods of treating TYK2-associated conditions are provided. La presente invención proporciona compuestos, composiciones de los mismos y métodos para usarlos. Los compuestos y las composiciones de los mismos que son útiles, por ejemplo, para dirigirse, inhibir y/o degradar TYK2. En determinadas modalidades, se proporcionan agentes inhibidores y/o degradantes de TYK2 y métodos para hacerlos. Más específicamente, se proporcionan agentes degradantes de TYK2, composiciones que comprenden agentes degradantes de TYK2 y métodos para tratar afecciones relacionadas con TYK2.