TETRAZOLE COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY
The present invention relates to compounds that are derivatives of Imatinib, have a phenylamino pyrimidine group and another 1,5-disubstituted tetrazole group within their structure, and have anti-inflammatory activity. Also, it relates to pharmaceutical compositions comprising said compounds and to...
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| creator | BAIZABAL AGUIRRE Víctor Manuel ROMERO DURÁN Marco Antonio CORTÉS GARCÍA Carlos Jesús |
| description | The present invention relates to compounds that are derivatives of Imatinib, have a phenylamino pyrimidine group and another 1,5-disubstituted tetrazole group within their structure, and have anti-inflammatory activity. Also, it relates to pharmaceutical compositions comprising said compounds and to a method for resolving the activation of inflammation in the Keap1-Nrf2 antioxidant-anti-inflammatory system.
La presente invención se refiere a compuestos que son derivados de Imatinib y que tienen dentro de su estructura un grupo fenilaminopirimidina y otro grupo tetrazol 1,5-disustituido y que además tienen actividad antiinflamatoria. La presente invención también se refiere a composiciones farmacéuticas que comprenden estos compuestos. Asimismo, la presente invención se refiere a un método para resolver la activación de la inflamación en el sistema antioxidante-antiinflamatorio Keap1-Nrf2. |
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La presente invención se refiere a compuestos que son derivados de Imatinib y que tienen dentro de su estructura un grupo fenilaminopirimidina y otro grupo tetrazol 1,5-disustituido y que además tienen actividad antiinflamatoria. La presente invención también se refiere a composiciones farmacéuticas que comprenden estos compuestos. Asimismo, la presente invención se refiere a un método para resolver la activación de la inflamación en el sistema antioxidante-antiinflamatorio Keap1-Nrf2.</description><language>eng ; spa</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240611&DB=EPODOC&CC=MX&NR=2024002794A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240611&DB=EPODOC&CC=MX&NR=2024002794A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BAIZABAL AGUIRRE Víctor Manuel</creatorcontrib><creatorcontrib>ROMERO DURÁN Marco Antonio</creatorcontrib><creatorcontrib>CORTÉS GARCÍA Carlos Jesús</creatorcontrib><title>TETRAZOLE COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY</title><description>The present invention relates to compounds that are derivatives of Imatinib, have a phenylamino pyrimidine group and another 1,5-disubstituted tetrazole group within their structure, and have anti-inflammatory activity. Also, it relates to pharmaceutical compositions comprising said compounds and to a method for resolving the activation of inflammation in the Keap1-Nrf2 antioxidant-anti-inflammatory system.
La presente invención se refiere a compuestos que son derivados de Imatinib y que tienen dentro de su estructura un grupo fenilaminopirimidina y otro grupo tetrazol 1,5-disustituido y que además tienen actividad antiinflamatoria. La presente invención también se refiere a composiciones farmacéuticas que comprenden estos compuestos. Asimismo, la presente invención se refiere a un método para resolver la activación de la inflamación en el sistema antioxidante-antiinflamatorio Keap1-Nrf2.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAOcQ0Jcozy93FVcPb3DfAP9XMJVgj3DPFQcPQL8dT19HPzcfT1dQzxD4pUcHQO8QzzDInkYWBNS8wpTuWF0twMSm6uIc4euqkF-fGpxQWJyal5qSXxvhFGBkYmBgZG5pYmjsZEKQIALMooJw</recordid><startdate>20240611</startdate><enddate>20240611</enddate><creator>BAIZABAL AGUIRRE Víctor Manuel</creator><creator>ROMERO DURÁN Marco Antonio</creator><creator>CORTÉS GARCÍA Carlos Jesús</creator><scope>EVB</scope></search><sort><creationdate>20240611</creationdate><title>TETRAZOLE COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY</title><author>BAIZABAL AGUIRRE Víctor Manuel ; ROMERO DURÁN Marco Antonio ; CORTÉS GARCÍA Carlos Jesús</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MX2024002794A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; spa</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BAIZABAL AGUIRRE Víctor Manuel</creatorcontrib><creatorcontrib>ROMERO DURÁN Marco Antonio</creatorcontrib><creatorcontrib>CORTÉS GARCÍA Carlos Jesús</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BAIZABAL AGUIRRE Víctor Manuel</au><au>ROMERO DURÁN Marco Antonio</au><au>CORTÉS GARCÍA Carlos Jesús</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TETRAZOLE COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY</title><date>2024-06-11</date><risdate>2024</risdate><abstract>The present invention relates to compounds that are derivatives of Imatinib, have a phenylamino pyrimidine group and another 1,5-disubstituted tetrazole group within their structure, and have anti-inflammatory activity. Also, it relates to pharmaceutical compositions comprising said compounds and to a method for resolving the activation of inflammation in the Keap1-Nrf2 antioxidant-anti-inflammatory system.
La presente invención se refiere a compuestos que son derivados de Imatinib y que tienen dentro de su estructura un grupo fenilaminopirimidina y otro grupo tetrazol 1,5-disustituido y que además tienen actividad antiinflamatoria. La presente invención también se refiere a composiciones farmacéuticas que comprenden estos compuestos. Asimismo, la presente invención se refiere a un método para resolver la activación de la inflamación en el sistema antioxidante-antiinflamatorio Keap1-Nrf2.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TETRAZOLE COMPOUNDS WITH ANTI-INFLAMMATORY ACTIVITY |
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