SUBCUTANEOUS FORMULATIONS OF ANTI-ABETA PROTOFIBRIL ANTIBODY AND METHODS OF USE THEREOF

Disclosed herein are methods of treating Alzheimer's disease, methods of reducing clinical decline in a subject having early Alzheimer's disease, methods of reducing brain amyloid level in a subject, methods of converting a subject from amyloid positive to amyloid negative, methods of prev...

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Hauptverfasser:	SACHDEV Pallavi, KOYAMA Akihiko, KANEKIYO Michio, VERBEL David, HAYATO Seiichi, DHADDA Shobha, REYDERMAN Larisa, GORDON Robert, KRAMER Lynn, IRIZARRY Michael, KAPLOW June, SWANSON Chad, LANDRY Ishani
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	SACHDEV Pallavi KOYAMA Akihiko KANEKIYO Michio VERBEL David HAYATO Seiichi DHADDA Shobha REYDERMAN Larisa GORDON Robert KRAMER Lynn IRIZARRY Michael KAPLOW June SWANSON Chad LANDRY Ishani
description	Disclosed herein are methods of treating Alzheimer's disease, methods of reducing clinical decline in a subject having early Alzheimer's disease, methods of reducing brain amyloid level in a subject, methods of converting a subject from amyloid positive to amyloid negative, methods of preventing Alzheimer's disease, the methods comprising subcutaneously administering an anti-AÎ² protofibril antibody. En el presente documento, se describen métodos para tratar la enfermedad de Alzheimer, métodos para reducir el deterioro clínico en un sujeto que tiene enfermedad de Alzheimer temprana, métodos para reducir el nivel de amiloide cerebral en un sujeto, métodos para convertir un sujeto de amiloide positivo en amiloide negativo, métodos para prevenir la enfermedad de Alzheimer, comprendiendo los métodos administrar por vía subcutánea un anticuerpo anti protofibrillas Aß.
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subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	SUBCUTANEOUS FORMULATIONS OF ANTI-ABETA PROTOFIBRIL ANTIBODY AND METHODS OF USE THEREOF
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