SYNTHESIS OF DELTA 9,11 STEROIDS

The present invention is directed to a process for the preparation of â¿¿9,11 steroids by deoxygenation of 9,11-epoxy steroids using HI. The disclosed process selectively forms â¿¿9,11 steroids such as Vamorolone and can also be used for steroid synthesis of â¿¿9,11 steroids in pharmaceutical purity...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MARTIN Marco, OLIVIERI Lauso, SCHÄFER Gabriel
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The present invention is directed to a process for the preparation of â¿¿9,11 steroids by deoxygenation of 9,11-epoxy steroids using HI. The disclosed process selectively forms â¿¿9,11 steroids such as Vamorolone and can also be used for steroid synthesis of â¿¿9,11 steroids in pharmaceutical purity. La presente invención está dirigida a un procedimiento para la preparación de esteroides ?9,11 mediante la desoxigenación de esteroides 9,11-epoxi usando HI; el procedimiento descrito forma selectivamente esteroides ?9,11 tales como vamorolona, y puede usarse también para la síntesis de esteroides ?9,11 en pureza farmacéutica.