LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR

The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune...

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Hauptverfasser: NEELAMKAVIL Santhosh, HENDRICK Charles, BRANCA Danila, COSTANTE Roberto, DEL RIZZO Sonia, BHANDARI Ashok, BIANCHI Elisabetta, RIEXINGER Douglas, ROSOLIA Federica, DANIEL James, PATCH Raymond J, SOMANI Sandeep, ZHANG Jing, LOLLOBRIGIDA Martina, TRAN Tran Trung, FREDERICK Brian, SUN Chengzao, BARROS Stephanie A
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creator NEELAMKAVIL Santhosh
HENDRICK Charles
BRANCA Danila
COSTANTE Roberto
DEL RIZZO Sonia
BHANDARI Ashok
BIANCHI Elisabetta
RIEXINGER Douglas
ROSOLIA Federica
DANIEL James
PATCH Raymond J
SOMANI Sandeep
ZHANG Jing
LOLLOBRIGIDA Martina
TRAN Tran Trung
FREDERICK Brian
SUN Chengzao
BARROS Stephanie A
description The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders. Included are various, highly-customizable peptide sequences to be tailored to treat a broad range of ailments. La presente invención se relaciona con nuevos inhibidores peptídicos lipídicos del receptor de interleucina-23 (IL-23R) o sales, solvatos y/u otras formas farmacéuticamente aceptables de estos, composiciones farmacéuticas, métodos y/o usos correspondientes de los inhibidores de IL-23R para el tratamiento de enfermedades inflamatorias autoinmunitarias y/o trastornos relacionados. Se incluyen varias secuencias de péptidos altamente personalizables que se adaptarán para tratar un amplio rango de doleEncias.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR
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