LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR

The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune...

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Hauptverfasser:	NEELAMKAVIL Santhosh, HENDRICK Charles, BRANCA Danila, COSTANTE Roberto, DEL RIZZO Sonia, BHANDARI Ashok, BIANCHI Elisabetta, RIEXINGER Douglas, ROSOLIA Federica, DANIEL James, PATCH Raymond J, SOMANI Sandeep, ZHANG Jing, LOLLOBRIGIDA Martina, TRAN Tran Trung, FREDERICK Brian, SUN Chengzao, BARROS Stephanie A
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders. Included are various, highly-customizable peptide sequences to be tailored to treat a broad range of ailments. La presente invención se relaciona con nuevos inhibidores peptídicos lipídicos del receptor de interleucina-23 (IL-23R) o sales, solvatos y/u otras formas farmacéuticamente aceptables de estos, composiciones farmacéuticas, métodos y/o usos correspondientes de los inhibidores de IL-23R para el tratamiento de enfermedades inflamatorias autoinmunitarias y/o trastornos relacionados. Se incluyen varias secuencias de péptidos altamente personalizables que se adaptarán para tratar un amplio rango de doleEncias.