COMPOSITIONS AND METHODS FOR DELIVERING MESSENGER RNA
The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions...
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| creator | JUDGE Adam HEYES James ABRAMS Michael J PALMER Lorne Ralph LAM Kieu Mong REID Stephen P YAWORSKI Edward D |
| description | The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.
La presente invención proporciona composiciones que comprenden moléculas de ácido nucleico, tales como moléculas de ARNm, encapsuladas dentro de las partículas lipídicas. Las composiciones son útiles, por ejemplo, para introducir las moléculas de ARNm en un sujeto humano donde se traducen para producir un polipéptido que funciona para aliviar uno o más síntomas de una enfermedad. |
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La presente invención proporciona composiciones que comprenden moléculas de ácido nucleico, tales como moléculas de ARNm, encapsuladas dentro de las partículas lipídicas. Las composiciones son útiles, por ejemplo, para introducir las moléculas de ARNm en un sujeto humano donde se traducen para producir un polipéptido que funciona para aliviar uno o más síntomas de una enfermedad.</description><language>eng ; spa</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES ; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NANOTECHNOLOGY ; PERFORMING OPERATIONS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES ; SPIRITS ; TRANSPORTING ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240125&DB=EPODOC&CC=MX&NR=2024000327A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240125&DB=EPODOC&CC=MX&NR=2024000327A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JUDGE Adam</creatorcontrib><creatorcontrib>HEYES James</creatorcontrib><creatorcontrib>ABRAMS Michael J</creatorcontrib><creatorcontrib>PALMER Lorne Ralph</creatorcontrib><creatorcontrib>LAM Kieu Mong</creatorcontrib><creatorcontrib>REID Stephen P</creatorcontrib><creatorcontrib>YAWORSKI Edward D</creatorcontrib><title>COMPOSITIONS AND METHODS FOR DELIVERING MESSENGER RNA</title><description>The present invention provides compositions comprising nucleic acid molecules, such as mRNA molecules, encapsulated within lipid particles. The compositions are useful, for example, to introduce the mRNA molecules into a human subject where they are translated to produce a polypeptide that functions to ameliorate one or more symptoms of a disease.
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NANOTECHNOLOGY PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES SPIRITS TRANSPORTING VINEGAR WINE |
| title | COMPOSITIONS AND METHODS FOR DELIVERING MESSENGER RNA |
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