INTERLEUKIN-15 BASED IMMUNOCYTOKINES

The present invention inter alia relates to immunocytokines involving IL-15 superagonists (based on IL-15 and the sushi domain of IL-15Rα) and an antibody. The invention also provides nucleic acids, vectors, methods and medical uses. La presente invención se refiere, inter alia, a inmunocitocinas q...

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Hauptverfasser: HOSKOVÁ Simona, NEDVEDOVA Eva, BÉCHARD David, BAMMERT Lukas, DE MARTYNOFF Guy Luc Michel, WALDMEIER Lorenz, BEERLI Roger Renzo, VALENTOVÁ Iva, MOEBIUS Ulrich, PECHOUCKOVÁ Sárka, KYRYCH SADILKOVA Lenka, ANTOSOVÁ Zuzana, ADKINS Irena
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present invention inter alia relates to immunocytokines involving IL-15 superagonists (based on IL-15 and the sushi domain of IL-15Rα) and an antibody. The invention also provides nucleic acids, vectors, methods and medical uses. La presente invención se refiere, inter alia, a inmunocitocinas que implican superagonistas de IL-15 (basados en IL-15 y el dominio de sushi de IL-15Ra) y un anticuerpo. La invención también proporciona ácidos nucleicos, vectores, métodos y usos médicos.