3,4-DIHYDRO-2,7-NAPHTHYRIDINE-1,6(2H,7H)-DIONES AS MEK INHIBITORS

The invention relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and comp...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	BOYS Mark Laurence, KNAPP Ellen Margaret, REN Li, COWDREY Connor James, KELLUM Alex Andrew, DAHLKE Joshua Ryan, WITKOS Faith Elizabeth, BLANCHE Sydney Taylor, O''LEARY Jacob Matthew, FULTON Jennifer Lynn, MORENO David Austin, ALLEN Shelley, BLAKE James Francis, DOERNER BARBOUR Patrick Michael, CLARK Wesley Dewitt
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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