OPTIMIZED ONCOLYTIC VIRUSES AND USES THEREOF

Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer t...

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Bibliographische Detailangaben
Hauptverfasser: TARAROVA Natalia D, CHUMAKOV Peter M, CHUMAKOV Stepan P, LIPATOVA Anastasia V, CHARLES Stephen A, KOMAR Anton A
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors. Se describen métodos para inhibir o reducir el crecimiento de tumores. Una composición que contiene al menos un virus oncolítico seleccionado se administra dentro de un tumor de un paciente. El virus mata las células cancerosas e induce una inmunidad antitumoral sistémica y duradera que también es compatible con otros tratamientos para el cáncer. También se describen métodos para crear virus sintéticos para atacar tumores cancerosos.