SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES

The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La invención proporciona composic...

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Hauptverfasser: KHOSSRAVI Mehrnaz, HART Scott Aaron, HABY Thomas Arthur, MURTHY Bindu Purnima, SANGHAVI Kinjal, ZHAO Xiaochen, BELLO Akintunde, VEZINA Heather Elizabeth, HUANG Masano, ARAS Urvi Ashish, ROY Amit, MANTRI Rao Venkatramana
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creator KHOSSRAVI Mehrnaz
HART Scott Aaron
HABY Thomas Arthur
MURTHY Bindu Purnima
SANGHAVI Kinjal
ZHAO Xiaochen
BELLO Akintunde
VEZINA Heather Elizabeth
HUANG Masano
ARAS Urvi Ashish
ROY Amit
MANTRI Rao Venkatramana
description The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La invención proporciona composiciones farmacéuticas que comprenden un anticuerpo anti-PD-1 o un anticuerpo anti-PD-L1 formuladas para administración subcutánea, en donde las composiciones farmacéuticas además comprenden una enzima endoglicosidasa hidrolasa, tal como una hialuronidasa.
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language eng ; spa
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES
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