SUBCUTANEOUS ADMINISTRATION OF PD1/PD-L1 ANTIBODIES

The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La invención proporciona composic...

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Bibliographische Detailangaben
Hauptverfasser:	KHOSSRAVI Mehrnaz, HART Scott Aaron, HABY Thomas Arthur, MURTHY Bindu Purnima, SANGHAVI Kinjal, ZHAO Xiaochen, BELLO Akintunde, VEZINA Heather Elizabeth, HUANG Masano, ARAS Urvi Ashish, ROY Amit, MANTRI Rao Venkatramana
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La invención proporciona composiciones farmacéuticas que comprenden un anticuerpo anti-PD-1 o un anticuerpo anti-PD-L1 formuladas para administración subcutánea, en donde las composiciones farmacéuticas además comprenden una enzima endoglicosidasa hidrolasa, tal como una hialuronidasa.