NOVEL INSECT INHIBITORY PROTEINS

Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4029, TIC4029_1, and TIC4029_8. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal protei...

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Bibliographische Detailangaben
Hauptverfasser: HOWE Arlene R, BOWEN David J, MEYER Jason, WEINER Brian E, CHAY Catherine A, MILLIGAN Jason S, MARENGO Matthew S
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4029, TIC4029_1, and TIC4029_8. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding pesticidal proteins of the TIC4029 class. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the TIC4029 class in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4029, TIC4029_1, and TIC4029_8 pesticidal proteins are also provided. Se revelan proteínas pesticidas que presentan actividad tóxica contra especies de plaga Lepidopteran, e incluyen, aunque no se limitan a, TIC4029, TIC4029_1, y TIC4029_8. Se proporcionan constructos ADN que contienen una secuencia de ácido nucleico recombinante que codifica una o más de las proteínas pesticidas reveladas. Se proporcionan plantas transgénicas, células de plantas, semillas, y partes de plantas resistentes a infestación Lepidopteran infestación que contienen secuencias de ácido nucleico recombinante que codifican proteínas pesticida de la clase TIC4029. También se proporcionan métodos para detectar la presencia de las secuencias de ácido nucleico recombinante o las proteínas de la clase TIC4029 en una muestra biológica, y métodos para controlar plagas de especie Lepidopteran usando cualquiera de las proteínas pesticidas TIC4029, TIC4029_1, y TIC4029_8.