SYSTEMS AND METHODS FOR PRODUCING DISEASE-ASSOCIATED PROTEIN COMPOSITIONS

The disclosure herein relates to in silico methods for reconstructing complete polypeptide and nucleic acid consensus sequences for novel biologically active protein dimers, including but not limited to antibodies that are useful for the treatment and diagnosis of a cancer, autoimmune condition, or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAKOCEVIC Goran, DE SANTIAGO DOMINGOS DE JESUS Ines, BIASCI Daniele, TOPTAS Berke, Cagkan
Format: Patent
Sprache:eng ; spa
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Beschreibung
Zusammenfassung:The disclosure herein relates to in silico methods for reconstructing complete polypeptide and nucleic acid consensus sequences for novel biologically active protein dimers, including but not limited to antibodies that are useful for the treatment and diagnosis of a cancer, autoimmune condition, or infectious disease. La descripción en la presente descripción se refiere a métodos in silico para reconstruir secuencias completas de consenso de polipéptidos y ácidos nucleicos para dímeros de proteínas biológicamente activos novedosos, que incluyen pero no se limitan a anticuerpos que son útiles para el tratamiento y diagnóstico de un cáncer, afección autoinmunitaria, o enfermedad infecciosa.