PROCESS OF REWORKING

The invention describes a process for reworking of a crystallization product comprising drying and homogenization. The crystallization product is crystalline [5-(methylsulfonyl)-2- {[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(tri fluoromethyl)-1,2-oxazol-3-5 yl]-3-azabicyclo[3.1.0]hex...

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Bibliographische Detailangaben
Hauptverfasser:	BARTA Albert Josef, GRIMM Julia Regina, BAER Katrin, GAO Joe Ju, ADACHI Masashi, NORDSTROM Fredrik Lars, BODENBACH Gisela, YANG Bing-shiou, WIESE Michael, SCHROEDER Daniela Maria, EGUSA Kenji, NAKATANI Manabu, MESSERSCHMID Roman Christian
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention describes a process for reworking of a crystallization product comprising drying and homogenization. The crystallization product is crystalline [5-(methylsulfonyl)-2- {[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(tri fluoromethyl)-1,2-oxazol-3-5 yl]-3-azabicyclo[3.1.0]hex-3-yl}methanone. The product is dried in a tray dryer or in a pan dryer und subsequently homogenized. La invención describe un proceso de reelaboración de un producto de cristalización que comprende el secado y la homogeneización. El producto de cristalización es [5-(metilsulfonil)-2-{[(2R)-1,1,1 -trifluoropropan-2-il]oxi}fenil]{(1R,5R)-1-[5-(trifluorometil)-1, 2-oxazol-3-il]-3-azabiciclo[3.1.0]hex-3-il}metanona cristalina. El producto se seca en un secador de bandejas o en un recipiente de secado y posteriormente se homogeneiza.