COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE

COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE

Provided herein are compounds and compositions thereof for modulating bis-phosphoglycerate mutase (BPGM) for treating sickle cell disease. Se proporcionan en la presente compuestos y composiciones de los mismos para modular la bis-fosfoglicerato mutasa (BPGM) y tratar las células de anemia falciform...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIU Jinyu, DESAI Kunal, HONG Vu, GUERTIN Kevin, FANG Zhong, JIANG John Ziqi, MUNSON Mark, LIM Sungtaek
Format: Patent
Sprache:eng ; spa
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided herein are compounds and compositions thereof for modulating bis-phosphoglycerate mutase (BPGM) for treating sickle cell disease. Se proporcionan en la presente compuestos y composiciones de los mismos para modular la bis-fosfoglicerato mutasa (BPGM) y tratar las células de anemia falciforme.