NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME

Provided herein are novel AAV capsids and recombinant AAV vectors comprising the same. In one embodiment, vectors employing a novel AAV capsid show increased transduction of a selected target tissue as compared to a prior art AAV. En el presente documento, se proporcionan cápsides AAV novedosas y ve...

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Bibliographische Detailangaben
Hauptverfasser:	MARTINO Richard Alexander, NAMBIAR Kalyani, WANG Qiang, WILSON James M, SIDRANE Jenny A
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are novel AAV capsids and recombinant AAV vectors comprising the same. In one embodiment, vectors employing a novel AAV capsid show increased transduction of a selected target tissue as compared to a prior art AAV. En el presente documento, se proporcionan cápsides AAV novedosas y vectores AAV recombinantes que las comprenden; en una forma de realización, los vectores que utilizan una nueva cápside de AAV demuestran una transducción mayor de un tejido diana seleccionado en comparación con un AAV anterior.