ANTIBODIES AGAINST ILT2 AND USE THEREOF

The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclos...

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Bibliographische Detailangaben
Hauptverfasser:	MANDEL Ilana, PERETZ Tsuri, BEN-MOSHE Tehila, SHULMAN Avidor, FRIDMAN-DROR Anna, SAPIR Yair, ALISHEKEVITZ Dror, GOLDSHTEIN Ilana, HAVES ZIV Dana, HAKIM Motti
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclosure. Methods of patient selection are also provided. La presente divulgación proporciona anticuerpos monoclonales anti-ILT2 o fragmentos de unión a antígeno de los mismos, así como composiciones farmacéuticas que comprenden los mismos y métodos para producir los mismos. También se proporcionan métodos para tratar el cáncer utilizando los anticuerpos o composiciones de la presente divulgación. También se proporcionan métodos para la selección de pacientes.