ANTIGEN BINDING PROTEIN

Provided herein are antigen binding proteins that specifically bind to BMP1, TLL1 and/or TLL2. Also provided are pharmaceutical compositions containing the antigen binding proteins. The antigen binding proteins and pharmaceutical compositions described herein can be used to treat diseases associated...

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Bibliographische Detailangaben
Hauptverfasser:	HARPEL Mark R, ZHANG Jian, HARRIS Carol A, CLARKSON Jane Elizabeth, DIMECH Caroline J
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are antigen binding proteins that specifically bind to BMP1, TLL1 and/or TLL2. Also provided are pharmaceutical compositions containing the antigen binding proteins. The antigen binding proteins and pharmaceutical compositions described herein can be used to treat diseases associated with fibrotic conditions or disorders as well as to promote muscle growth and improve muscle function. En la presente se proporcionan proteínas de unión a antígeno que se unen específicamente a BMP1, TLL1 y/o TLL2. También se proporcionan composiciones farmacéuticas que contienen las proteínas de unión a antígeno. Las proteínas de unión a antígeno y composiciones farmacéuticas descritas en la presente se pueden utilizar para tratar enfermedades asociadas con afecciones o trastornos fibróticos, así como para promover el crecimiento muscular y mejorar la función muscular.