ANTI-BETACELLULIN ANTIBODIES, FRAGMENTS THEREOF, AND MULTI-SPECIFIC BINDING MOLECULES

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BT...

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Bibliographische Detailangaben
Hauptverfasser:	TWAROG Michael Zbigniew, BIGELOW Chad Eric, CHASTAIN James Edgar, ETEMAD-GILBERTSON Bijan Alexandre, CLARK Kirk Lee, STEFANIDAKIS Michael, GHOSH Joy Gispati, QIU Yubin, HAUBST Nicole, NGUYEN Andrew Anh, IYER Ganesh Rajan, HANKS Shawn Michael, MOKER Nina, TOKSOZ Engin, CARRION Ana Maria, POOR Stephen Hendrick, RANGASWAMY Nalini Velamur
Format:	Patent
Sprache:	eng ; spa
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety. La presente invención proporciona anticuerpos anti-BTC, métodos de producción de dichos anticuerpos, composiciones farmacéuticas que comprenden dichos anticuerpos y métodos de uso de dichos anticuerpos. La presente invención además proporciona moléculas de unión multiespecíficas, por ejemplo, anticuerpos biespecíficos, que comprenden un resto de unión a BTC y un resto de unión anti-VEGF.