GLUTARIMIDE DERIVATIVE FOR OVERCOMING RESISTANCE TO STERIODS

The present invention relates to medicine, particularly to a novel drug that is effective for treating illnesses associated with aberrant interferon gamma signaling, such as Sjögren syndrome, dermatomyositis, systemic lupus erythematosus, or systemic sclerosis, as well as in the treatment of patients suffering from a cough, and for treating disorders in patients having steroid resistance, such as asthma, rheumatoid arthritis, systemic lupus erythematosus, and diseases of the gastrointestinal tract by using a 1-(2-(1Н-imidazol-4-yl)ethyl)piperidine-2,6-dione compound (formula I). The invention provides for creating a novel effective drug for overcoming steroid resistance. La presente invención se refiere a la medicina, en particular, a un nuevo fármaco efectivo para el tratamiento de enfermedades relacionadas con la señalización aberrante de interferón gamma, tal como síndrome de Sjögren, dermatomiositis, lupus eritematoso sistémico o esclerosis sistémica; para el tratamiento de pacientes que padecen tos; y para el tratamiento de trastornos en pacientes resistentes a los esteroides, tal como asma, artritis reumatoide, lupus eritematoso sistémico y enfermedades gastrointestinales, al administrar un compuesto 1-(2-(1H-imidazol-4-il)etil) piperidin-2,6-diona (ver Fórmula); la invención proporciona la creación de un nuevo fármaco efectivo para superar la resistencia a los esteroides.