IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE

The present application relates to an imidazolinone derivative and the use thereof in medicine, and specifically relates to a pyrimidine derivative as represented by general formula (I), or a stereoisomer, solvate, metabolite, prodrug, pharmaceutically acceptable salt or co-crystal thereof, a pharma...

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Bibliographische Detailangaben
Hauptverfasser: YAN Jie, HE Lvxue, XU Xuezhen, LEI Feiquan, HE Yang, SUN Yi, SU Guizhuan, WEI Yonggang, CHU Hongzhu, LIU Bing, WANG Meiwei
Format: Patent
Sprache:eng ; spa
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Zusammenfassung:The present application relates to an imidazolinone derivative and the use thereof in medicine, and specifically relates to a pyrimidine derivative as represented by general formula (I), or a stereoisomer, solvate, metabolite, prodrug, pharmaceutically acceptable salt or co-crystal thereof, a pharmaceutical composition containing same and the use of the compound or the composition of the present application in the preparation of drugs for treating cancers. La presente solicitud se relaciona con derivados de imidazolidinona y su uso médico, y en particular se relaciona con derivados de pirimidina representados por la fórmula general (I), o estereoisómeros, solvatos, metabolitos, profármacos, sales farmacéuticamente aceptables o cocristales de los mismos, una composición farmacéutica que comprende éstos, y el uso del compuesto o composición farmacéutica según la presente solicitud en la fabricación de un medicamento para el tratamiento del cáncer. (ver Fórmula).